Machilin G and four neolignans from young fruits of Magnolia denudata show various degrees of inhibitory activity on nitric oxide (NO) production.
نویسندگان
چکیده
Denudatin A and B, denudadione B, fargesone A and machilin G were isolated from Magnolia denudata. These compounds showed inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1. Some but not all of the inhibition of NO production by machilin G, and denudatin A and B was apparently through the decreased expression of the inducible NO synthase (iNOS) gene.
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 72 10 شماره
صفحات -
تاریخ انتشار 2008